America's #1 Lotion Tissue. Click Add to Cart now; Pack includes 4 Family Boxes (124 Tissues per Box) of Puffs Plus Lotion Facial Tissues; Puffs softest, most cushiony tissue, with a touch of moisturizing lotion, to protect your nose; Our family size box is requested most by classrooms so it's perfect for back-to-school; Puffs Plus Lotion helps soothe irritated noses by locking in moisture better than regular tissues