Puffs Plus Lotion is our most soothing facial tissue with lotion in a mega cube box. Puffs Plus Lotion is the perfect tissue for when sore or runny noses need some extra softness for any cold, flu, or allergy. Puffs Plus Lotion facial tissues lock in moisture better, to help soothe irritated skin commonly caused from rough or thin tissues. It's no wonder that Puffs Plus Lotion is America's #1 selling Lotion Tissue brand. A nose in need deserves Puffs indeed!